We construct a q-model structure, an h-model structure and an m-model structure on multipointed d-spaces and on flows. The two q-model structures are combinatorial and left determined and they coincide with the combinatorial model structures already known on these categories. The four other model structures (the two m-model structures and the two h-model structures) are accessible. We give an example of multipointed d-space and of flow which are not cofibrant in any of the model structures. We explain why the m-model structures, Quillen equivalent to the q-model structure of the same category, are better behaved than the q-model structures.

BACKGROUND: There is no convenient cheap pragmatic experimental model for Nonalcoholic Fatty Liver Disease (NAFLD) /Nonalcoholic Steatohepatitis (NASH). Objective: Our objective was to create a pragmatic model of NAFLD/NASH.METHODS: Sprague-Dawley rats were fed a high-fat, high sugar homemade diet ad libitum for seven weeks. The high-fat, high sugar diet included 59% of energy derived from fat, 30% from carbohydrates, and 11% from protein. Serum levels of fasting glucose, triglyceride, cholesterol, liver enzymes, insulin, and hepatic tumor necrosis factor-alpha (TNF-a) gene expression were determined. Hepatic histology was examined by H & E stain.RESULTS: Rats fed the high-fat, high sugar diet developed hepatic steatosis, and a moderate inflammation, which was associated with increased serum levels of liver enzymes, glucose, insulin, triglyceride, cholesterol, and hepatic TNF-a gene expression.CONCLUSION: This rat model resembles the key features of human NAFLD/NASH and provides a simple pragmatic experimental model for elucidating the disease prevention and treatment.

The personalized local mobile search aims at finding the right on the spot information that is most relevant to the user's requests. It is implemented as a mobile application where the user can access nearby places based on his/ her current location. In Today's technology driven world user profiles are the virtual representation of each user and they include a variety of user information such as personal, interest and preference data. These profiles are the outcome of the user profiling process and they are essential to service personalization. The user profile based personalization approach can be applied to enhance the power of mobile local search for local spots and contributes to a significant convenience in location-based mobile searching. The system takes the user information such as personal, health, entertainment and choice of preference and these parameters are passed to Google Maps API key for personalized query processing. As a result, the user will get prominent services rather than closing one.

To participate in tourism activities as a cultural right and an opportunity for their social integration, people with disabilities face various environmental barriers which affect their tendency to participate in tourism activities. Therefore, in the present study, an attempt has been made to identify and investigate the environmental barriers and limitations (micro and macro environment) faced by these people for participating in tourism activities. This study is carried out using mixed-method in two stages of qualitative (identifying the environmental indicators and factors of accessible tourism development for people with physical disabilities through in-depth, semi-structured interview with scientific and executive experts) and quantitative (Designing the questionnaires by researchers based on indicators obtained from the qualitative stage and distributing them among 150 tourists with disabilities in Tehran). Making use of open and central coding with Maxqda software, the content analysis of the first stage interviews was carried out and 2 main categories, 12 main concepts and 45 sub-concepts were identified. The quantitative stage was carried out using the partial least squares method and SmartPLS3 software. Consequently, planning and policy-making, transportation, tourism places, tourism products and services, human resources, information, technology and equipment, were identified as micro-environmental factors (tourism industry). Also planning and policy-making, economic, physical, cultural, and social factors were identified as the macro-environment factors of accessible tourism development for people with physical disabilities.

In this paper first we define the morphism between geometric spaces in two different types. We construct two categories of U-GESP and L-GESP from geometric spaces then investigate some properties of the two categories, for instance U-GESP is topological. The relation between hypergroups and geometric spaces is studied. By constructing the category SNS-Hv of Hv-groups we answer the question that which construction of hyperstructures on the category of sets has free object in the sense of universal property. At the end we define the category of geometric Hypergroups and we study its relation with the category of hypergroup.

To View The Abstract, Please Click On PDF File.

Background: Individuals’ experiences following addiction abstinence may have different meanings from the former addict’s perspective, demanding careful scrutiny to understand such experiences.Objectives: This study aimed to explore and explain the meaning of the lived experiences of addicts after sobriety.Patients and Methods: This descriptive phenomenological study aimed to describe the experiences of individuals who had stopped using drugs. The participants were 10 members of narcotics anonymous (NA) in Lenjan, Iran, who were recruited using the purposive sampling method. To gather the data, unstructured, in-depth interviews were carried out. The interviews were recorded on cassette tapes with the consent of the participants, and the collected data were analyzed using Colaizzi’s method.Results: The results of this study were presented in the form of 48 codes and included the four main themes of detour, gateway, metamorphosis, and leadership. These represent the general structure of the individuals’ lives after recovery.Conclusions: Our findings revealed that specific factors, such as recall of sustained suffering in the course of recovery, members’contribution, being part of a community, participation in collective classes, feelings of equality and co-leveledness, observation of others’ success, and rethinking, played significant roles in addiction recovery.